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  2 - 2Europa League 2021-22 Leicester City Stadium Leicester vs SSC Napoli |
 2 - 3Europa League 2021-22 Stadio Diego Armando Maradona SSC Napoli vs Spartak Mosca |
 3 - 0Europa League 2021-22 Stadio Diego Armando Maradona SSC Napoli vs Legia Varsavia |
1 - 4Europa League 2021-22 Pepsi Arena Legia Varsavia vs SSC Napoli |
2 - 1Europa League 2021-22 Stadio Spartak Spartak Mosca vs SSC Napoli |
3 - 2Europa League 2021-22 Stadio Diego Armando Maradona SSC Napoli vs Leicester |
 1 - 1Europa League 2021-22 Camp Nou Barcellona FC vs SSC Napoli |
2 - 4Europa League 2021-22 Stadio Diego Armando Maradona SSC Napoli vs Barcellona FC |
| Pos | Club | P | W | D | L | F | A | GD | Pts |
|---|---|---|---|---|---|---|---|---|---|
| 1 | SSC Napoli | 8 | 3 | 2 | 3 | 18 | 15 | 3 | 11 |
| 2 | Spartak Mosca | 5 | 2 | 1 | 2 | 9 | 9 | 0 | 7 |
| 3 | Legia Varsavia | 4 | 2 | 0 | 2 | 3 | 7 | -4 | 6 |
| 4 | Leicester | 5 | 1 | 2 | 2 | 9 | 10 | -1 | 5 |
