| 2021-05-23 15:00:2723/05/2021 | SSC Napoli  | 1 - 1 | Hellas Verona | Serie A | 2020-21 | | Riepilogo | - |
| 2021-05-16 12:30:3816/05/2021 | Fiorentina AC | 0 - 2 | SSC Napoli | Serie A | 2020-21 | | Riepilogo | - |
| 2021-05-11 20:45:3711/05/2021 | SSC Napoli | 5 - 1 | Udinese | Serie A | 2020-21 | | Riepilogo | - |
| 2021-05-08 15:00:5108/05/2021 | Spezia C. | 1 - 4 | SSC Napoli | Serie A | 2020-21 | | Riepilogo | - |
| 2021-05-02 15:00:0202/05/2021 | SSC Napoli | 1 - 1 | Cagliari Calcio | Serie A | 2020-21 | | Riepilogo | - |
| 2021-04-26 18:30:0826/04/2021 | Torino FC | 0 - 2 | SSC Napoli | Serie A | 2020-21 | | Riepilogo | - |
| 2021-04-22 20:45:1622/04/2021 | SSC Napoli | 5 - 2 | SS Lazio | Serie A | 2020-21 | | Riepilogo | - |
| 2021-04-18 20:45:2918/04/2021 | SSC Napoli | 1 - 1 | Inter FC | Serie A | 2020-21 | | Riepilogo | - |
| 2021-04-11 15:00:4411/04/2021 | UC Sampdoria | 0 - 2 | SSC Napoli | Serie A | 2020-21 | | Riepilogo | - |
| 2021-04-07 18:45:0807/04/2021 | Juventus FC | 2 - 1 | SSC Napoli | Serie A | 2020-21 | | Riepilogo | - |
| 2021-04-03 15:00:5903/04/2021 | SSC Napoli | 4 - 3 |  Crotone FC | Serie A | 2020-21 | | Riepilogo | - |
| 2021-03-21 20:45:1221/03/2021 | AS Roma | 0 - 2 | SSC Napoli | Serie A | 2020-21 | | Riepilogo | - |
| 2021-03-14 20:45:2514/03/2021 | AC Milan  | 0 - 1 | SSC Napoli | Serie A | 2020-21 | | Riepilogo | - |
| 2021-03-07 20:45:3307/03/2021 | SSC Napoli | 3 - 1 | Bologna BC | Serie A | 2020-21 | | Riepilogo | - |
| 2021-03-03 18:30:5103/03/2021 | US Sassuolo  | 3 - 3 | SSC Napoli | Serie A | 2020-21 | | Riepilogo | - |
| 2021-02-28 18:00:5228/02/2021 | SSC Napoli | 2 - 0 |  Benevento | Serie A | 2020-21 | | Riepilogo | - |
| 2021-02-25 18:55:3425/02/2021 | SSC Napoli | 2 - 1 |  Granada CF | Europa League | 2020-21 | | Riepilogo | - |
| 2021-02-21 18:00:0021/02/2021 | Atalanta B.C. | 4 - 2 | SSC Napoli | Serie A | 2020-21 | | Riepilogo | - |
| 2021-02-18 21:00:4418/02/2021 | Granada CF | 2 - 0 | SSC Napoli | Europa League | 2020-21 | | Riepilogo | - |
| 2021-02-13 18:00:4713/02/2021 | SSC Napoli | 1 - 0 | Juventus FC | Serie A | 2020-21 | | Riepilogo | - |
| 2021-02-10 20:45:1510/02/2021 | Atalanta B.C. | 3 - 1 | SSC Napoli | Coppa Italia | 2020-21 | | Riepilogo | - |
| 2021-02-03 20:45:3803/02/2021 | SSC Napoli | 0 - 0 | Atalanta B.C. | Coppa Italia | 2020-21 | | Riepilogo | - |
| 2021-01-31 18:00:2031/01/2021 | SSC Napoli | 2 - 0 | Parma Calcio | Serie A | 2020-21 | | Riepilogo | - |
| 2021-01-28 21:00:5328/01/2021 | SSC Napoli | 4 - 2 | Spezia C. | Coppa Italia | 2020-21 | | Riepilogo | - |
| 2021-01-24 15:00:1524/01/2021 | Hellas Verona | 3 - 1 | SSC Napoli | Serie A | 2020-21 | | Riepilogo | - |
| 2021-01-20 21:00:2620/01/2021 | SSC Napoli | 0 - 2 | Juventus FC | Supercoppa Italiana | 2020-21 | | Riepilogo | - |
| 2021-01-17 12:30:4417/01/2021 | SSC Napoli | 6 - 0 | Fiorentina AC | Serie A | 2020-21 | | Riepilogo | - |
| 2021-01-13 17:45:3413/01/2021 | SSC Napoli | 3 - 2 | Empoli FC | Coppa Italia | 2020-21 | | Riepilogo | - |
| 2021-01-10 15:00:0210/01/2021 | Udinese | 1 - 2 | SSC Napoli | Serie A | 2020-21 | | Riepilogo | - |
| 2021-01-06 18:00:2306/01/2021 | SSC Napoli | 1 - 2 | Spezia C. | Serie A | 2020-21 | | Riepilogo | - |
| 2021-01-03 15:00:3303/01/2021 | Cagliari Calcio | 1 - 4 | SSC Napoli | Serie A | 2020-21 | | Riepilogo | - |
| 2020-12-23 20:45:4023/12/2020 | SSC Napoli | 1 - 1 | Torino FC | Serie A | 2020-21 | | Riepilogo | - |
| 2020-12-20 20:45:0120/12/2020 | SS Lazio | 2 - 0 | SSC Napoli | Serie A | 2020-21 | | Riepilogo | - |
| 2020-12-16 20:45:2116/12/2020 | Inter FC | 1 - 0 | SSC Napoli | Serie A | 2020-21 | | Riepilogo | - |
| 2020-12-13 15:00:3613/12/2020 | SSC Napoli | 2 - 1 | UC Sampdoria | Serie A | 2020-21 | | Riepilogo | - |
| 2020-12-10 18:55:1510/12/2020 | SSC Napoli | 1 - 1 | Real Sociedad | Europa League | 2020-21 | | Riepilogo | - |
| 2020-12-06 18:00:4306/12/2020 | Crotone FC | 0 - 4 | SSC Napoli | Serie A | 2020-21 | | Riepilogo | - |
| 2020-12-03 21:00:1003/12/2020 | AZ Alkmaar  | 1 - 1 | SSC Napoli | Europa League | 2020-21 | | Riepilogo | - |
| 2020-11-29 20:45:4729/11/2020 | SSC Napoli | 4 - 0 | AS Roma | Serie A | 2020-21 | | Riepilogo | - |
| 2020-11-26 21:00:5626/11/2020 | SSC Napoli | 2 - 0 | HNK Rijeka | Europa League | 2020-21 | | Riepilogo | - |
| 2020-11-22 20:45:4522/11/2020 | SSC Napoli | 1 - 3 | AC Milan | Serie A | 2020-21 | | Riepilogo | - |
| 2020-11-08 18:00:5208/11/2020 | Bologna BC | 0 - 1 | SSC Napoli | Serie A | 2020-21 | | Riepilogo | - |
| 2020-11-05 18:55:1205/11/2020 | HNK Rijeka | 1 - 2 | SSC Napoli | Europa League | 2020-21 | | Riepilogo | - |
| 2020-11-01 18:00:4901/11/2020 | SSC Napoli | 0 - 2 | US Sassuolo | Serie A | 2020-21 | | Riepilogo | - |
| 2020-10-29 21:00:2229/10/2020 | Real Sociedad | 0 - 1 | SSC Napoli | Europa League | 2020-21 | | Riepilogo | - |
| 2020-10-25 15:00:4625/10/2020 | Benevento | 1 - 2 | SSC Napoli | Serie A | 2020-21 | | Riepilogo | - |
| 2020-10-22 18:55:3022/10/2020 | SSC Napoli | 0 - 1 | AZ Alkmaar | Europa League | 2020-21 | | Riepilogo | - |
| 2020-10-17 15:00:5317/10/2020 | SSC Napoli | 4 - 1 | Atalanta B.C. | Serie A | 2020-21 | | Riepilogo | - |
| 2020-09-27 18:00:2027/09/2020 | SSC Napoli | 6 - 0 | Genoa C.F.C. | Serie A | 2020-21 | | Riepilogo | - |
| 2020-09-19 20:45:3719/09/2020 | Parma Calcio | 0 - 2 | SSC Napoli | Serie A | 2020-21 | | Riepilogo | - |
